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Enteric Hyperoxaluria (EH)

A guide for patients & families.

What is EH and what causes it?

Enteric Hyperoxaluria (EH) is a medical condition caused by increased absorption of oxalate from foods in the digestive tract (also called the gut or intestines).

It is caused by various underlying conditions that affect the intestines, such as inflammatory bowel diseases (IBD) like Crohn’s disease, as well as malabsorptive conditions like celiac disease, cystic fibrosis, and chronic pancreatitis. Some weight loss surgeries, such as Roux-en-Y gastric bypass, can also increase the risk of developing EH.

The prevalence of Enteric Hyperoxaluria (EH) has been estimated at 5-24% of all patients with gastrointestinal diseases associated with malabsorption. EH is a frequent complication of inflammatory bowel diseases (IBD), ileal resection and Roux-en-Y gastric bypass (RYGB) and is well-known to cause kidney stones, and nephrocalcinosis. EH can also contribute to chronic kidney disease (CKD) and kidney failure.

Illustration: oxalate from food is absorbed in the intestines and passes to the kidneys

Who helps with diagnosis & care?

Care often involves:

Gastroenterologists

– digestion

Nephrologists

– kidneys

Registered dietitians

– nutrition

Primary care providers

– coordinated care

How EH is treated

There is no single treatment. These steps can help protect the kidneys:

Nutrition & Lifestyle

  • Eat less oxalate
  • Include calcium with meals
  • Reduce fat if needed

Hydration

Drink enough fluids to help remove oxalate from the body.

Monitoring

Your doctors may check urine oxalate, kidney function, and other labs.

Resources & support

Oxalate Food Guide

The Oxalosis and Hyperoxaluria Foundation (OHF) offers this guide showing oxalate levels in foods and drinks.

Care Team Guidance

Your doctor or dietitian can give recommendations for your situation.

Download the guide

Enteric Hyperoxaluria (EH): A Guide for Patients & Families (PDF)

EH can be managed with the right information, care team, and support.

Learn more about EH from the Oxalosis & Hyperoxaluria Foundation: Enteric Hyperoxaluria on ohf.org

Disclaimer: This guide is for educational purposes only and does not replace medical advice. Always consult your healthcare provider for diagnosis and treatment.

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